1 pathological expression of the germ cell testicular tumors and their biology
Báo cáo y học: "Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells" pps
... producing the chemokine CCL5 [39,40] The memory population may be further divided by the expression or loss of expression of CCR7 [12] We and others have previously shown that the majority of T cells ... values of CCL5, and error bars one standard deviation Phenotype of CCL5+ T cells within the joint CD8+ T cells of the effector and memory compartments have been shown to express high levels of the ... their own recruitment We analysed the phenotype of the CCL5+CCR5+CD8 T cell population within the joint Several studies have proposed stages of differentiation for effector and memory CD8 T cells:...
- 11
- 508
- 0
Tài liệu Project (written version):“The problems of the “Citibus” (bus operating company) and their possible solutions. Drawing a contract.” doc
... and consequently they not their best, other thing which should be mentioned is the wrong schedule of the bus routes (which doesn’t take a proper account of the interests of the passengers); and ... change the cituation for better (increase the passing capacity of the roads that doesn’t cope with the growing number of cars and other carriers, build new roads and rearrange the traffic within the ... comfortanle during the trip So the documents we offer you are the special colred tickets The second way of increasing the motivation of our drivers is to organize the competition among the drivers,...
- 5
- 682
- 0
Báo cáo khoa học: Expression of the Drosophila melanogaster ATP synthase a subunit gene is regulated by a transcriptional element containing GAF and Adf-1 binding sites pptx
... processing of the D melanogaster a-F1-ATPase transcript The expression of the a-F1-ATPase gene during development is coordinated with the expression of the nuclearencoded b-F1-ATPase gene and the mitochondrial-encoded ... footprinting of the 5¢ upstream region of the a-F1-ATPase gene and found that the combination of GAF and Adf-1 binding sites is present both in other Drosophila species (D yakuba and D pseudoobscura) and ... under the control of the actin 5C promoter The GAGA factor stimulated at least threefold the activity of the promoter in constructs )397/+86 and )146/+86, but had no effect on the activity of the...
- 11
- 532
- 0
Báo cáo khoa học: Cell type-specific transgene expression of the prion protein in Xenopus intermediate pituitary cells ppt
... suggesting that the level of GFP–PrPC transgene expression was dependent on the colour of the background of the animal The fusion protein was found only in the NIL and not in the AL of black- and white-adapted ... physiological manipulation of the biosynthetic and secretory activity of the melanotrope cell In this study, we combined the unique properties of the melanotrope cell with the technique of stable Xenopus ... Discussion The aim of the present study was to investigate the intracellular fate of PrPC by examining for the first time its biosynthesis in the secretory pathway of neuroendocrine cells in vivo and the...
- 16
- 431
- 0
Báo cáo khoa học: Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1 pdf
... cells The expression of rPhl p in insect cells was optimized by infecting Sf9 cells with different amounts of virus and by expression for various periods Aliquots of the culture supernatants and cell ... 1, the cDNA coding for the mature allergen was expressed in baculovirus-infected insect cells An expression strategy was chosen which led to the secretion of the recombinant allergen into the cell ... insect cell- expressed Phl p and, to a lower degree, in the nPhl p preparations Biochemical and biophysical characterization of insect -cell expressed Phl p The molecular mass of insect cell- expressed...
- 11
- 355
- 0
Báo cáo khoa học: Functional expression of the quinoline 2-oxidoreductase genes (qorMSL) in Pseudomonas putida KT2440 pUF1 and in P. putida 86-1 Dqor pUF1 and analysis of the Qor proteins doc
... from Hanes plots Determination of the metal contents of the Qor proteins, and detection of the nucleotide moiety of the molybdenum cofactor The contents of molybdenum and iron were determined by ... cleaves 364-bp upstream of the start codon of qorM, and DraIII, that cleaves 8-bp downstream of the stop codon of qorL After removing the 3¢ overhang and filling the 5¢ overhang of the plasmid with T4 ... indicated in Fig 4B The absence of Mo(V)signals reveals the g2-component of FeSII It is noted that the g-factors of the FeSI and II signals of the Qor proteins from the wild-type strain and from P putida...
- 11
- 724
- 0
Báo cáo Y học: Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo potx
... explain the lack of the effect of the transgene on the size of the latter depot [16,17]; this is also associated with the differential effect of the transgene on in situ fatty acid synthesis in the ... multilocular cells in white fat, the morphology of mitochondria and the mitochondrial content of the unilocular cells were affected by the transgene The morphometric study of subcutaneous white fat of the ... young but not adult mice, and they were absent from epididymal fat, regardless of either the age of the animals, or the genotype Therefore, the results document further that the resistance against...
- 10
- 555
- 0
báo cáo hóa học:" Decrease in the expression of the type 1 PTH/PTHrP receptor (PTH1R) on chondrocytes in animals with osteoarthritis" potx
... preparation and macroscopic and histological grading of OA SFW participated in the conception of the study and supervised the protocol COT was responsible for the initial conception of the research ... In summary, the present study shows a decrease in the expression of the PTH1R receptor over the time course of OA Further studies are needed to determine 1) the physiologic role of this receptor ... that chondrocytes of the radial zone occupied twice the volume and surface area of the chondrocytes of the superficial zone but were 10 times more synthetically active [27] We hypothesize that PTH1R...
- 6
- 440
- 0
Báo cáo khoa học: "Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas" potx
... in the degradation of the stroma The expression of MMP-2 was present basically in the neoplastic cells In the case of MMP-9 most of the cases were negative both tumoral and reactive cells The expression ... molecular and cellular components of the vascular wall On the other hand, 12 cases of the present series showed a more intense expression of TIMP-1 in epithelial cells, mainly the mucosal gland, whose ... In addition to the high positivity of neoplastic cells to the immunophenotype of NK (CD 56) cells and cytoplasmic CD3, the lack of rearrangement of the T-clonal receptor cells and positivity...
- 9
- 247
- 0
Báo cáo y học: ":The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1" ppsx
... RAGE expression in FLS cultures in our experiments and may be relevant to the over -expression of RAGE on RA synovial tissues However, the exact mechanism of RAGE over -expression in the milieu of ... pathway of IL-17-induced RAGE production and expression, we tested the effect of Act-1 shRNA on RAGE production We produced Act-1 shRNA and confirmed the inhibitory effect of Act-1 shRNA on Act-1 expression ... criteria of the American College of Rheumatology [18] Informed consent was provided according to the Declaration of Helsinki and obtained from all patients Approval by the ethical committee of the...
- 12
- 343
- 0
Retrovirology Research BioMed Central Open Access In vivo expression of the HBZ gene of HTLV-1 doc
... value of tax/value of HPRT HTLV-1 HBZ mRNA load = value of HBZ/value of HPRT We used aliquots of the same standard MT-2 cDNA preparation for all assays and the correlation values of standard ... observed in 60.7% of HAM/TSP patients (34 out of 56), 71.1% of HCs (27 out of 38) and 30.0% of ATL patients (3 out of 10) The medians are represented by horizontal lines and the statistical differences ... at least the biclonal integration of HTLV-1 proviral DNA The incidence of multibands in our cases (two out of ten: 20%) was comparable with the data by Kamihira et al (17.8%) The Page of 11 (page...
- 11
- 393
- 0
Báo cáo y học: "Polarized expression of the membrane ASP protein derived from HIV-1 antisense transcription in T cells" potx
... membrane [22] The presence of ASP was detected in the cytoplasm and the nucleus in the vicinity of the cell membranes However, the nucleolar localization of ASP is unexpected since the nucleolus ... above The morphology of the cell was assessed by NDIC White bars correspond to a scale of 10 μm ASP is expressed in infected Jurkat T cells Before analyzing the expression of ASP in infected cells, ... scale of 10 μm or in the antisense direction from the 3’ LTR Such a mechanism allows the synthesis of a complex proteome from the proviral genome integrated into the cell chromosome Although the...
- 13
- 324
- 0
Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt
... that of other class RNRs or, instead, is a result of the interaction of the R2F with the inactivated (oxidized) form of the R1E We consider the first option unlikely Under these circumstances, the ... In the present study, we report data on homologous expression of the nrdF gene of C ammoniagenes strain ATCC 6872 This is the first report of the successful purification of high amounts of the ... reproduces the centre of the experimental spectrum reasonably well It cannot, however, explain the remarkably broad wings of the signal The broad lineshape and the enhanced relaxation properties of the...
- 14
- 872
- 0
Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf
... less in size at the time of diagnosis The events occurred in black women and two in women of other observed rates of occurrence of tumors of 1.0 cm or smaller were races Of the seven tumors that ... use of mammography has resulted in the more frequent detection of DCIS In view of the cost involved and the effort required to diagnose these tumors and in light of the debate about both the ... cm were 2.63 and 1.04 per 1000 women, respeccancer was assessed by means of a comparison of the rates of the tively The rates of occurrence of tumors of 2.1–3.0 cm were occurrence of that disease...
- 18
- 645
- 0
Tài liệu Engineering Mechanics - StaticsChapter 1Problem 1-1 Represent each of the following combinations of units in the correct SI form using an appropriate prefix: (a) m/ms (b) μkm (c) ks/mg (d) km⋅ μN Units Used: μN = 10−6N kmμkm = 109−6Gs = 10 s pptx
... = 150 N Problem 2-17 Determine the magnitude and direction of the resultant force F R Express the result in terms of the magnitudes of the components F and F and the angle φ Solution: F R = F ... Problem 2-20 The plate is subjected to the forces acting on members A and B as shown Determine the magnitude of the resultant of these forces and its direction measured clockwise from the positive ... Problem 2-41 Determine the magnitude and direction of the resultant FR = F + F2 + F of the three forces by summing the rectangular or x, y components of the forces to obtain the resultant force...
- 1,119
- 1,071
- 2
Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... and colony formation assays confirmed the active role of miR-23a in the growth promotion of malignant cells The fundamental function of miRNAs is to regulate their targets by direct cleavage of ... on the expression of IL6R by RT-PCR and western blot, and found an inverse correlation between miR-23a and IL6R expression at both the mRNA and protein levels To confirm the direct regulation of ... complementary to the miR-23a seed region Three binding sites of miR-23a were found in the 3¢ UTR of IL6R mRNA (Fig 3A) To confirm that miR-23a can bind to these regions and suppress the expression of the target...
- 9
- 541
- 0
Tài liệu Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes doc
... the standard deviation of the two replicates (B and C) RAW cells were cotransfected with the pCI ⁄ ESE-1 expression vector, the NF-jB p50 and p65 expression vectors or a combination thereof and ... observed across the different studies as well as the similarity of the recognition sites of the NFAT and Ets factors led us to investigate the potential involvement of the epithelial specific ... transcription factors as the mutation of the CRE site within the COX-2 promoter or the expression of a dominant negative mutant of CREB reduces inducibility of the COX-2 promoter [9,12–14] The transcription...
- 12
- 519
- 0
Tài liệu Báo cáo Y học: Purification, characterization, cloning, and expression of the chicken liver ecto-ATP-diphosphohydrolase pot
... apical membranes of the oxyntic-peptic cells [37] The distribution of the ectoATPDase on these epithelial cells is distinctly different from the other ATPDase in the E-ATPase family, the CD39s [13,17,19] ... concentration of mM at pH 7.4 On the other hand, the CaADPase activity is 80% of the MgADPase activity at a divalent ion-ADP concentration of mM (data not shown) The ATPase and ADPase activities of the ... numbers are on the right side of the figure The transmembranous domains of the protein at the N- and C-terminus are shaded The five apyrase conserved regions (ACRs) are underlined and in bold The 10 cysteine...
- 10
- 694
- 0
Báo cáo khoa học: Cloning and expression of the first nonmammalian interleukin-11 gene in rainbow trout Oncorhynchus mykiss pdf
... procedures Cell lines and cell culture Four rainbow trout cell lines were used in these studies; the mononuclear cell line RTS-11 [33], the gonad cell line RTG [34], the liver cell line RTL [35] and ... RTS cells, as seen in the northern blot (Fig 7), and is the largest of the known IL-11 molecules Interestingly, the trout IL-11 transcript has four potential poly(A) signals (AATAAA), two of them ... fibroblasts, lung epithelial cell lines and endometrial epithelial and stromal cells TGF-b has been shown to stimulate IL-11 production in a number of cell types, including lung epithelial cells, fibroblasts,...
- 12
- 511
- 0
Báo cáo Y học: Expression of the V-ATPase proteolipid subunit of Acetabularia acetabulum in a VMA3-deficient strain of Saccharomyces cerevisiae and study of its complementation pdf
... for the subunits A and B of V-ATPase The intracellular localization of these isoforms and the combination of the isoforms is yet to be determined We are now trying to express fusion proteins of ... ratio of the three proteins could not be estimated Forgac described in a recent minireview [21] that the VO domain consisted of six copies of the c/c0 subunits and single copies of the other subunits ... overexpressed by induction, accumulation of the dye in the vacuoles of both transformants was observed, and the intensity was weaker than that in the transformants of the other four genes constructed in...
- 8
- 391
- 0
Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu